The Lost "Easter Egg" in This Week's Episode of Weeds
We're not sure exactly who watches Weeds anymore, but Eric Lange (Radzinsky from LOST) has been featured in the past few episodes. In this episode we see that he has been staying in motel room 108.
[There was a video here]
Nerds like me may remember that the character Radzinsky in LOST was the person who designed the hatch where he, Desmond and others were forced to press a button every 108 to discharge electromagnetism building up within the hatch.